Good quality pharmaceutical raw material Prednisolone base CAS NO.50-24-8

Description

Name:prednisolone

Chemical name:11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione

CAS NO.: 50-24-8

EINECS:200-021-7

Chemical Structure

Molecular formula:C21H28O5

Molecular Weight:360.45

Standard:USP32

Functuon

[1]it's use for the treatment of a wide range of inflammatory and auto-immune conditions
[2]such as asthma,uveitis, pyoderma gangrenosum, rheumatoid arthritis, ulcerative colitis, temporal arteritis and Crohn's disease, Bell's palsy, multiple sclerosis
[3] cluster headaches, vasculitis, acute lymphoblastic leukemia and autoimmune hepatitis, systemic lupus erythematosus, and dermatomyositis.

Application

Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, chloramphenicol is still widely used because it is exceedingly inexpensive and readily available.

The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and a plastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.