- Product Details
Keywords
- Lorlatinib
- PF-6463922
- PF6463922
Quick Details
- ProName: PF-6463922 Lorlatinib
- CasNo: 1454846-35-5
- Molecular Formula: C18H13ClF4N2O3
- Appearance: white powder
- Application: used by athletes to assist in training...
- DeliveryTime: immediately
- PackAge: aluminum foil bag
- Port: HK, Shanghai, Shenzhen
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Storage: cool and dry place
- Transportation: EMS,DHL,HK post,EUB,ETK,NL post,German...
- LimitNum: 1 Gram
Superiority
Details
Loratinib, also known as PF-06463922, is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene 1 (Ros1), with potential antineoplastic activity. Upon administration, ALK/ROS1 inhibitor PF-06463922 binds to and inhibits both ALK and ROS1 kinases. The kinase inhibition leads to disruption of ALK- and ROS1-mediated signaling and eventually inhibits tumor cell growth in ALK- and ROS1-overexpressing tumor cells. In addition, PF-06463922 is able to cross the blood brain barrier.
Packing and shipping