Genistein CAS NO.446-72-0

【NAME】：Genistein
【SYNONYMS】：5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 
【SPEC.】：98%
【TEST METHOD】： HPLC 
【PLANT SOURCE】：Genista tinctoria Linn., Sophora subprostrala Chun et T.Chen.
【CAS NO.】：446-72-0
【MOLECULAR FORMULAR & MOLECULAR MASS】：C15H10O5   270.2
【STRUCTURAL FORMULA】：                         
【CHARACTERISTIC】：Genistein is soluble in chloroform:methanol(1:1[v:v],10 mg/ml),yielding a clear, faint to light yellow solution. Stock solutions of genistein in DMSO(up to a concentration of 100 mM) have been prepared.Genistein is practically insoluble in cold water;slightly soluble in hot water, hot ethanol, and hot methanol and soluble in hot 80% ethanol, hot 80% methanol,hot acetone, and pyridine.
【PHARMACOLOGY】：Double-blind, placebo-controlled studies have found that genistein may be helpful for preventing heart disease and preventing or treating osteoporosis . Genistein may additionally improve blood sugar control in people with pre- diabetes. Weaker evidence suggests potential benefits in cancer prevention, cancer treatment, and amyotrophic lateral sclerosis (ALS). Isoflavone mixtures containing genistein have undergone considerably more study than genistein alone. Mixed isoflavones have shown promise for most of the conditions just mentioned, as well as menopausal symptoms and cyclic mastalgia.
【CHEMICAL ANALYSIS 】