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Home > Products >  Abiraterone / Abiraterone Intermediates

Abiraterone / Abiraterone Intermediates CAS NO.154229-19-3

  • Min.Order: 10 Gram
  • Payment Terms: T/T,MoneyGram
  • Product Details

Keywords

  • Abiraterone Intermediate
  • Abiraterone Intermediate powder
  • CAS 154229-19-3

Quick Details

  • ProName: Abiraterone / Abiraterone Intermediate...
  • CasNo: 154229-19-3
  • Molecular Formula: C24H31NO
  • Appearance: white powder
  • Application: Abiraterone (CB-7598, CB7598, CB 7598)...
  • DeliveryTime: immediately
  • PackAge: aluminum foil bag
  • Port: HK, Shanghai, Shenzhen
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • Storage: cool and dry place
  • Transportation: email: wonda-chem@outlook.com
  • LimitNum: 10 Gram

Superiority

1.high quality:

quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.

2.reasonable price:

we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.

3.low moq:

no worry about the low moq, our moq is 1 gram or even lower.

4.good service.

fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.

5. fast shipping and secure courier.

we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.

 

Details

Description                                           

Product Name:Abiraterone

CAS No .154229-19-3

Formula:C24H31NO 

Molecular Weight:1202.84 

CAS No.154229-19-3

Density:1.016 g/cm3

Melting Point:148-151°C

Boiling Point:1293.8 °Cat 760 mmHg

Flash Point:736.3 °C

Solubility:ethanol: 30 mg/mL

Appearance:White Powder

Introduction                                          

Abiraterone (CB-7598, CB7598, CB 7598) is a potent steroidal cytochrome P450 17alpha-hydroxylase-17,20-lyase (CYP17) inhibitor with an IC50 at 4 nM. Abiraterone is used in treatment of prostate cancer.

Abiraterone is the active metabolite of abiraterone acetate, which is an orally active acetate ester of the steroidal compound abiraterone with antiandrogen activity. Abiraterone acetate was approved by the U.S. Food and Drug Administration (FDA) in April 2011. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. Abiraterone is a drug used in castration-resistant prostate cancer (formerly hormone-resistant or hormone-refractory prostate cancer) -- i.e., prostate cancer not responding to androgen deprivation or treatment with antiandrogens. It is formulated as the prodrug abiraterone acetate and marketed under the trade name Zytiga.

COA                                                       

Items

Specifications

Results

Appearance

White or off-white solid

Complies

Identification

H-NMR

Complies

Melting point

223-233°C

224.3-226.2°C

Loss on drying

no more than 1.0%

0.5%

Residue on ignition

<0.2%

0.07%

Purity (HPLC)

no less than 99.0%

99.6% 

 

 

 

 

Packing and shipping 

 

 

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