China (Mainland)
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Good Price/Top Quality 99.0%, Ezetimibe Powder CAS NO.163222-33-1
- Min.Order: 10 Gram
- Payment Terms: T/T,
- Product Details
Keywords
- Ezetimibe Powder
- Ezetimibe
- CAS 163222-33-1
Quick Details
- ProName: Good Price/Top Quality 99.0%, Ezetimib...
- CasNo: 163222-33-1
- Molecular Formula: C24H21F2NO3
- Appearance: white powder
- Application: Ezetimibe is a kind of new selective c...
- DeliveryTime: immediately
- PackAge: aluminum foil bag
- Port: HK, Shanghai, Shenzhen
- ProductionCapacity: 100 Kilogram/Month
- Purity: 99%
- Storage: cool and dry place
- Transportation: email: wonda-chem@outlook.com
- LimitNum: 10 Gram
Superiority
1.high quality:
quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.
2.reasonable price:
we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.
3.low moq:
no worry about the low moq, our moq is 1 gram or even lower.
4.good service.
fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.
5. fast shipping and secure courier.
we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.
Details
Product name: Ezetimibe
Other name: Ezetimide
Specification: 99%
Specification:
| Item | Specifications | Results |
| Appearance | White to off-white powder | Complies |
| Identification | A. IR : Similar to Reference Substance | Complies |
| B. Meets the requirement | Complies | |
| Specific Rotation | -25°~ -30° | -27° |
| Water | Not more than 0.5% | 0.10% |
| Any single other impurity | Not more than 0.1% | 0.03% |
| Total impurities | Not more than 1.0% | 0.10% |
| Assay | 98.5%~102.0% | 99.80% |
| Conclusion | The results conforms with enterprise standards | |
Function:
Ezetimibe is a new class of selective cholesterol absorption inhibitors that inhibits the delivery of small intestine to the diet and bile to the intestine by binding to the small vesicle membrane protein (relative molecular mass 145X103) in the small intestine brush border membrane. The absorption of cholesterol lowers the cholesterol content in serum and liver. Unlike bile acid chelating agents, ezetimibe does not affect the absorption of cholesterol esters, other terpenoids (such as taurocholic acid), triacylglycerols, and fat-soluble vitamins. Its pharmacological action is independent of the inhibition of acetyl-CoA cholesterol acetyltransferase (ACAT) and the expression of LDL receptor (scavenger receptor). After being absorbed, ezetimibe is bound to glucuronic acid in the liver and then circulated through the liver and intestine, and is almost exclusively localized to small intestinal mucosal cells.
