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99% pure high quality Anti-inflammatory analgesic drugs Indometacin CAS NO.53-86-1
- Min.Order: 100 Gram
- Payment Terms: T/T,
- Product Details
Keywords
- Indometacin
- Indometacin powder
- CAS 53-86-1
Quick Details
- ProName: 99% pure high quality Anti-inflammator...
- CasNo: 53-86-1
- Molecular Formula: C19H16ClNO4
- Appearance: white powder
- Application: Anti-inflammatory
- DeliveryTime: within 3 working days upon payment
- PackAge: aluminum foil bag, drum
- Port: HK, Shanghai, Shenzhen
- ProductionCapacity: 500 Kilogram/Month
- Purity: 99%
- Storage: cool and dry place
- Transportation: email: wonda-chem@outlook.com
- LimitNum: 100 Gram
Superiority
1.high quality:
quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.
2.reasonable price:
we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.
3.low moq:
no worry about the low moq, our moq is 1 gram or even lower.
4.good service.
fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.
5. fast shipping and secure courier.
we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.
Details
Product Description
Indomethacin, an antiinflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis. Other studies show indomethacin to stabilize cholesterol-dependent nanoclusters and enhance phase separation in biological membranes, which could consequentially effect plasma membrane assembled cell signaling cascades. Indomethacin is an activator of PPAR α.
Specification
|
Product Name |
Indomethacin |
MFG. Date |
Dec.12.2015 |
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|
Batch NO. |
HS13-068 |
EXP. Date |
Dec.11.2018 |
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Batch quantity |
300kg |
Analysis Date |
Dec.18.2015 |
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Standard |
BP2005 |
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Items |
Specification |
Results |
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Characters |
White crystalline powder ,parctically insoluble in water, sparingly soluble in alcohol |
Conforms |
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Identification |
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A.Melting point |
158-162°C |
158.5-160.0°C |
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B.Absorption at 318nm |
170-190 |
185.19 |
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C. |
Conforms to the requirement |
Conforms |
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D. |
Conforms to the requirement |
Conforms |
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E. |
Conforms to the requirement |
Conforms |
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Related substances(TLC) |
Not more than 0.5% |
<0.5% |
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Heavy metals |
Not more than 20ppm |
<20ppm |
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Loss on drying |
Not more than 0.5% |
0.13% |
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Sulphated Ash |
Not more than 0.1% |
0.07% |
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Assay |
98.5%-100.5% |
99.8% |
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Conclusion:Complies with EP7 |
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Function and Application
Indometacin (INN and BAN) or indomethacin (AAN, USAN and former BAN) is a non-steroidal anti-inflammatory drug(NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling. It works by inhibiting the production of prostaglandins, molecules known to cause these symptoms.
It is marketed under more than twelve different trade names.
Packing and shipping
